Millipore/AB5471P |抗信号素3F抗体/AB5471P/100µ；G
市场价：
¥6980.00
美元价：
4188.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB5471P |
| Replaces | AB5471 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-Semaphorin3FAntibody |
| ProductInformation | |
|---|---|
| Format | AffinityPurified |
| Control |
|
| Presentation | AffinityPurifiedimmunoglobulin.Liquidin0.02MPhosphatebufferwith0.25MNaCland0.1%sodiumazide. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainfor1yearat2–8°Cfromdateofshipment.Aliquottoavoidrepeatedfreezingandthawing.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | SyntheticpeptidefromhumanSemaphorin3F(CatalognumberAG363).(TPWTQTQAVRFRFSRATDGALRPM). |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | RecognizesSemaphorin3F(Sema3F),recombinantandpurifiedprotein.ByWesternblottheantibodyrecognizesaproteinof90kDaintotalextractsfromtissueculturecellsproducingSema3F.Semaphorin3Fisexpressedubiquitouslywithhigherlevelsinlung,brain,spleen,muscleandheart. |
| SpeciesReactivity |
|
| SpeciesReactivityNote | ThisantibodymayalsoreactwithmousebecauseofextremelyhighsequenceconservationintheSEM3Fprotein. |
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Thesemaphorinsareafamilyofproteinsthatareinvolvedinsignaling.Allthefamilymembershaveasecretionsignal,a500-aminoacidsemadomain,and16conservedcysteineresidues(Kolodkinetal.,1993[PubMed8269517]).Sequencecomparisonshavegroupedthesecretedsemaphorinsinto3generalclasses,allofwhichalsohaveanimmunoglobulindomain.ThesemaphorinIIIfamily,consistingofhumansemaphorinIII(SEMA3A;MIM603961),chickencollapsin,andmousesemaphorinsA,D,andE,allhaveabasicdomainattheCterminus.Chickencollapsincontributestopathfindingbyaxonsduringdevelopmentbyinhibitingextensionofgrowthcones(Luoetal.,1993[PubMed8402908])throughaninteractionwithacollapsinresponsemediatorproteinofrelativemolecularmass62K(CRMP62)(Goshimaetal.,1995[PubMed7637782]),aputativehomologofanaxonalguidanceassociatedUNC33geneproduct(MIM601168).SEMA3FisasecretedmemberofthesemaphorinIIIfamily.[suppliedbyOMIM] |
| GeneSymbol |
|
| PurificationMethod | ImmunoAffinityPurified |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:Q13275#Mayplayaroleincellmotilityandcelladhesion. SIZE:785aminoacids;88381Da SUBCELLULARLOCATION:Secreted(Bysimilarity). TISSUESPECIFICITY:Expressedabundantlybutdifferentiallyinavarietyofneuralandnonneuraltissues.Thereishighexpressioninmammarygland,kidney,fetalbrain,andlungandlowerexpressioninheartandliver. DEVELOPMENTALSTAGE:Detectedasearlyasembryonicday10. SIMILARITY:SwissProt:Q13275##Belongstothesemaphorinfamily.&Contains1Ig-likeC2-type(immunoglobulin-like)domain.&Contains1Semadomain. |
| MolecularWeight | 90kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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