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Millipore/AB10522 | Anti-Neuropilin-2 Antibody/AB10522/100 µL
Millipore/AB10522 | Anti-Neuropilin-2 Antibody/AB10522/100 µL
市场价:
¥7180.00
美元价:
4308.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB10522 |
| Replaces | AB9160 |
| Description | Anti-Neuropilin-2Antibody |
| AlternateNames |
|
| BackgroundInformation | TherearetwoformsofNeuropilin:Neuropilin-1andNeuropilin-2.Thesearenon–tyrosinekinasereceptorsthatbindtoVEGFandsemaphorins(SEMA3A,SEMA3B,andSEMA3F)andplayanimportantroleinthecriticalfunctioningofthenervoussystem.Neuropilin-2isexpressedintumorcells,andmatureanddevelopingendothelialcellsandvascularsmoothmusclecells.Thisexpressionhasbeenassociatedwithtumorangiogenesisandprogression. |
| ProductInformation | |
|---|---|
| Format | Serum |
| Control |
|
| Presentation | UnpurifiedRabbitSerumcontaining0.05%SodiumAzide. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Stablefor1yearat-20°Cfromdateofreceipt. HandlingRecommendations:Uponreceiptandpriortoremovingthecap,centrifugethevialandgentlymixthesolution.Aliquotintomicrocentrifugetubesandstoreat-20°C.Avoidrepeatedfreeze/thawcycles,whichmaydamageIgGandaffectproductperformance. |
| Applications | |
|---|---|
| Application | DetectNeuropilin-2usingthisAnti-Neuropilin-2AntibodyvalidatedforuseinWB,IH,IP&IF. |
| KeyApplications |
|
| BIOLOGicalInformation | |
|---|---|
| Immunogen | His-taggedpartialrecombinantratNeuropilin-2protein. |
| Epitope | Unknown |
| Host | Rabbit |
| Specificity | ThisantibodyrecognizesNeuropilin-2. |
| Isotype | IgG |
| SpeciesReactivity |
|
| SpeciesReactivityNote | Proventoreactwithmouse. |
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| GeneSymbol |
|
| PurificationMethod | Unpurified |
| UniProtNumber | |
| UniProtSummary | FUNCTION:Highaffinityreceptorforsemaphorins3C,3F,VEGF-165andVEGF-145isoformsofVEGF,andthePLGF-2isoformofPGF. SUBUNITSTRUCTURE:HeterodimerwithNRP1Probable.BindsPLXNB1Bysimilarity. SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein. TISSUESPECIFICITY:FoundincertainneuronalpopulationsoftheCNSandinothernon-neuronaltissuesincludingmesenchymaltissueliningintheribs. DEVELOPMENTALSTAGE:Theexpressionpatternisverydynamicandisdevelopmentallyregulated. SEQUENCESIMILARITIES:Belongstotheneuropilinfamily. Contains2CUBdomains. Contains2F5/8typeCdomains. Contains1MAMdomain. |
| MolecularWeight | 130kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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