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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/AB10522 | Anti-Neuropilin-2 Antibody/AB10522/100 µL
商品详细Millipore/AB10522 | Anti-Neuropilin-2 Antibody/AB10522/100 µL
Millipore/AB10522 | Anti-Neuropilin-2 Antibody/AB10522/100 µL
Millipore/AB10522 | Anti-Neuropilin-2 Antibody/AB10522/100 µL
商品编号: AB10522
品牌: 密理博
市场价: ¥7180.00
美元价: 4308.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberAB10522
ReplacesAB9160
DescriptionAnti-Neuropilin-2Antibody
AlternateNames
  • Vascularendothelialcellgrowthfactor165receptor2
  • neuropilin2
  • receptorforVEGF165andsemaphorinsclass3
  • vascularendothelialgrowthfactor-165receptor2
BackgroundInformationTherearetwoformsofNeuropilin:Neuropilin-1andNeuropilin-2.Thesearenon–tyrosinekinasereceptorsthatbindtoVEGFandsemaphorins(SEMA3A,SEMA3B,andSEMA3F)andplayanimportantroleinthecriticalfunctioningofthenervoussystem.Neuropilin-2isexpressedintumorcells,andmatureanddevelopingendothelialcellsandvascularsmoothmusclecells.Thisexpressionhasbeenassociatedwithtumorangiogenesisandprogression.
ProductInformation
FormatSerum
Control
  • MouseP1braintissuelysate
PresentationUnpurifiedRabbitSerumcontaining0.05%SodiumAzide.
StorageandShippingInformation
StorageConditionsStablefor1yearat-20°Cfromdateofreceipt.
HandlingRecommendations:Uponreceiptandpriortoremovingthecap,centrifugethevialandgentlymixthesolution.Aliquotintomicrocentrifugetubesandstoreat-20°C.Avoidrepeatedfreeze/thawcycles,whichmaydamageIgGandaffectproductperformance.
Applications
ApplicationDetectNeuropilin-2usingthisAnti-Neuropilin-2AntibodyvalidatedforuseinWB,IH,IP&IF.
KeyApplications
  • WesternBlotting
  • Immunohistochemistry
  • Immunoprecipitation
  • Immunofluorescence
BIOLOGicalInformation
ImmunogenHis-taggedpartialrecombinantratNeuropilin-2protein.
EpitopeUnknown
HostRabbit
SpecificityThisantibodyrecognizesNeuropilin-2.
IsotypeIgG
SpeciesReactivity
  • Mouse
SpeciesReactivityNoteProventoreactwithmouse.
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
GeneSymbol
  • NRP2
  • NP2
  • NPN2
  • PRO2714
  • VEGF165R2
  • VEGF1265R2
  • 1110048P06Rik
PurificationMethodUnpurified
UniProtNumber
UniProtSummaryFUNCTION:Highaffinityreceptorforsemaphorins3C,3F,VEGF-165andVEGF-145isoformsofVEGF,andthePLGF-2isoformofPGF.

SUBUNITSTRUCTURE:HeterodimerwithNRP1Probable.BindsPLXNB1Bysimilarity.

SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein.

TISSUESPECIFICITY:FoundincertainneuronalpopulationsoftheCNSandinothernon-neuronaltissuesincludingmesenchymaltissueliningintheribs.

DEVELOPMENTALSTAGE:Theexpressionpatternisverydynamicandisdevelopmentallyregulated.

SEQUENCESIMILARITIES:Belongstotheneuropilinfamily.

Contains2CUBdomains.

Contains2F5/8typeCdomains.

Contains1MAMdomain.
MolecularWeight130kDa
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。