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Millipore/AB10522 | Anti-Neuropilin-2 Antibody/AB10522/100 µL

Millipore/AB10522 | Anti-Neuropilin-2 Antibody/AB10522/100 µL
市场价:
¥7180.00
美元价:
4308.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | AB10522 |
Replaces | AB9160 |
Description | Anti-Neuropilin-2Antibody |
AlternateNames |
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BackgroundInformation | TherearetwoformsofNeuropilin:Neuropilin-1andNeuropilin-2.Thesearenon–tyrosinekinasereceptorsthatbindtoVEGFandsemaphorins(SEMA3A,SEMA3B,andSEMA3F)andplayanimportantroleinthecriticalfunctioningofthenervoussystem.Neuropilin-2isexpressedintumorcells,andmatureanddevelopingendothelialcellsandvascularsmoothmusclecells.Thisexpressionhasbeenassociatedwithtumorangiogenesisandprogression. |
ProductInformation | |
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Format | Serum |
Control |
|
Presentation | UnpurifiedRabbitSerumcontaining0.05%SodiumAzide. |
StorageandShippingInformation | |
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StorageConditions | Stablefor1yearat-20°Cfromdateofreceipt. HandlingRecommendations:Uponreceiptandpriortoremovingthecap,centrifugethevialandgentlymixthesolution.Aliquotintomicrocentrifugetubesandstoreat-20°C.Avoidrepeatedfreeze/thawcycles,whichmaydamageIgGandaffectproductperformance. |
Applications | |
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Application | DetectNeuropilin-2usingthisAnti-Neuropilin-2AntibodyvalidatedforuseinWB,IH,IP&IF. |
KeyApplications |
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BIOLOGicalInformation | |
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Immunogen | His-taggedpartialrecombinantratNeuropilin-2protein. |
Epitope | Unknown |
Host | Rabbit |
Specificity | ThisantibodyrecognizesNeuropilin-2. |
Isotype | IgG |
SpeciesReactivity |
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SpeciesReactivityNote | Proventoreactwithmouse. |
AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
GeneSymbol |
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PurificationMethod | Unpurified |
UniProtNumber | |
UniProtSummary | FUNCTION:Highaffinityreceptorforsemaphorins3C,3F,VEGF-165andVEGF-145isoformsofVEGF,andthePLGF-2isoformofPGF. SUBUNITSTRUCTURE:HeterodimerwithNRP1Probable.BindsPLXNB1Bysimilarity. SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein. TISSUESPECIFICITY:FoundincertainneuronalpopulationsoftheCNSandinothernon-neuronaltissuesincludingmesenchymaltissueliningintheribs. DEVELOPMENTALSTAGE:Theexpressionpatternisverydynamicandisdevelopmentallyregulated. SEQUENCESIMILARITIES:Belongstotheneuropilinfamily. Contains2CUBdomains. Contains2F5/8typeCdomains. Contains1MAMdomain. |
MolecularWeight | 130kDa |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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