Millipore/05-480 |抗Eck/EphA2抗体，克隆D7/05-480/200和micro；G
市场价：
¥8020.00
美元价：
4812.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | 05-480 |
| BrandFamily | Upstate |
| TradeName |
|
| Description | Anti-Eck/EphA2Antibody,cloneD7 |
| AlternateNames |
|
| BackgroundInformation | EPHandEPH-relatedreceptorshavebeenimplicatedinmediatingdevelopmentalevents,particularlyinthenervoussystem.ReceptorsintheEPHsubfamilytypicallyhaveasinglekinasedomainandanextracellularregioncontainingaCys-richdomainand2fibronectintypeIIIrepeats.Theephrinreceptorsaredividedinto2groupsbasedonthesimilarityoftheirextracellulardomainsequencesandtheiraffinitiesforbindingephrin-Aandephrin-Bligands. Proteinkinasesareenzymesthattransferaphosphategroupfromaphosphatedonor,generallythegphosphateofATP,ontoanacceptoraminoacidinasubstrateprotein.Bythisbasicmechanism,proteinkinasesmediatemostofthesignaltransductionineukaryoticcells,regulatingcellularmetabolism,transcription,cellcycleprogression,cytoskeletalrearrangementandcellmovement,apoptosis,anddifferentiation. |
| ProductInformation | |
|---|---|
| Format | Purified |
| Control |
|
| Presentation | PurifiedmousemonoclonalIgG1inbuffercontaining0.2MTris-glycine,pH7.4,0.15MNaCl,with0.05%sodiumazideand30%glycerol. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Stablefor1yearat-20°Cfromdateofreceipt. HandlingRecommendations: Uponreceipt,andpriortoremovingthecap,centrifugethevialandgentlymixthesolution.Aliquotintomicrocentrifugetubesandstoreat-20°C.Avoidrepeatedfreeze/thawcycles,whichmaydamageIgGandaffectproductperformance.NOTE:VariABIlityinfreezertemperaturesbelow-20°Cmaycauseglycerol-containingsolutionstobecomefrozenduringstorage. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Nativeproteinisolatedbypurificationofphosphotyrosine-containingproteins.CloneD7. |
| Clone | D7 |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Mouse |
| Specificity | ThisantibodyrecognizesEpithelialCellKinase(Eck/EphA2),Mr140kDa |
| Isotype | IgG1 |
| SpeciesReactivity |
|
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Thisgenebelongstotheephrinreceptorsubfamilyoftheprotein-tyrosinekinasefamily.EPHandEPH-relatedreceptorshavebeenimplicatedinmediatingdevelopmentalevents,particularlyinthenervoussystem.ReceptorsintheEPHsubfamilytypicallyhaveasinglekinasedomainandanextracellularregioncontainingaCys-richdomainand2fibronectintypeIIIrepeats.Theephrinreceptorsaredividedinto2groupsbasedonthesimilarityoftheirextracellulardomainsequencesandtheiraffinitiesforbindingephrin-Aandephrin-Bligands.Thisgeneencodesaproteinthatbindsephrin-Aligands. |
| GeneSymbol |
|
| PurificationMethod | ProteinGPurified |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P29317#Receptorformembersoftheephrin-Afamily.Bindstoephrin-A1,-A3,-A4and-A5. SIZE:976aminoacids;108254Da SUBUNIT:InteractswithSLA(Bysimilarity).InteractswithINPPL1/SHIP2. SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein. TISSUESPECIFICITY:Expressedmosthighlyintissuesthatcontainahighproportionofepithelialcells,e.g.,skin,intestine,lung,andovary. SIMILARITY:SwissProt:P29317##Belongstotheproteinkinasesuperfamily.Tyrproteinkinasefamily.Ephrinreceptorsubfamily.&Contains2fibronectintype-IIIdomains.&Contains1proteinkinasedomain.&Contains1SAM(sterilealphamotif)domain. |
| MolecularWeight | 140kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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