Millipore/MAB366 |抗MAP1B抗体，克隆AA6/MAB366/100µ；L
市场价：
¥7180.00
美元价：
4308.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | MAB366 |
| BrandFamily | Chemicon® |
| TradeName |
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| Description | Anti-MAP1BAntibody,cloneAA6 |
| AlternateNames |
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| ProductInformation | |
|---|---|
| Format | Ascites |
| Presentation | Ascites.Liquidcontaining15mMsodiumazide. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainat-20°Cinundilutedaliquotsforupto12months.Avoidrepeatedfreeze/thawcycles. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Ratbrainmicrotubule-associatedprotein. |
| Clone | AA6 |
| Host | Mouse |
| Specificity | ReactsspecificallywithMAP1B(MAP5)byimmunoblot.Showsselectivestainingofdendritictreesthroughoutthebrain.Nocross-reactivityobservedtootherMAPsortubulin. MonoclonalAnti-MAP1bisimmunospecificforMAP1b(alsoknownasMAP5,MAPIXorMAP1.2;Riedereretal.,1986;Tuckeretal.,1988)asdeterminedbyanimmunoblotassay.Additionofantibodytomicrotubuleproteinsbeforepolymerizationresultsinabnormallyshort(butotherwisemorphologicallynormal)microtubules. |
| Isotype | IgG1 |
| SpeciesReactivity |
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| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Thisgeneencodesaproteinthatbelongstothemicrotubule-associatedproteinfamily.Theproteinsofthisfamilyarethoughttobeinvolvedinmicrotubuleassembly,whichisanessentialstepinneurogenesis.TheproductofthisgeneisaprecursorpolypeptidethatpresumablyundergoesproteolyticprocessingtogeneratethefinalMAP1BheavychainandLC1lightchain.Geneknockoutstudiesofthemousemicrotubule-associatedprotein1Bgenesuggestedanimportantroleindevelopmentandfunctionofthenervoussystem. |
| GeneSymbol |
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| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P46821#ThefunctionofbrainMAPSisessentiallyunknown.PhosphorylatedMAP1Bmayplayaroleinthecytoskeletalchangesthataccompanyneuriteextension.PossIBLyMAP1BBindstoatleasttwotubulinsubunitsinthepolymer,andthisbridgingofsubunitsmightbeinvolvedinnucleatingmicrotubulepolymerizationandinstABIlizingmicrotubules. SIZE:2468aminoacids;270620Da SUBUNIT:3differentlightchains,LC1,LC2andLC3,canassociatewithMAP1AandMAP1Bproteins.LC1interactswiththeamino-terminalregionofMAP1B.InteractswithANP32A(Bysimilarity). DOMAIN:SwissProt:P46821HasahighlybasicregionwithmanycopiesofthesequenceKKEEandKKEI/V,repeatedbutnotatfixedintervals,whichisresponsibleforthebindingofMAP1Btomicrotubules. PTM:LC1isgeneratedfromMAP1Bbyproteolyticprocessing.&PhosphorylateduponDNAdamage,probablybyATMorATR. SIMILARITY:BelongstotheMAP1family. |
| PhysicochemicalInformation |
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| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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