Millipore/AB5971 | Anti-HuD Antibody/AB5971/100 µg
市场价：
¥6980.00
美元价：
4188.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB5971 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-HuDAntibody |
| ProductInformation | |
|---|---|
| Format | AffinityPurified |
| Presentation | Affinitypurifiedimmunoglobulin.Precipitatedantibodyinasolutionof50%saturatedammoniumsulfateandPBScontainingnopreservatives. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainunopenedvialat-70°Cforupto6months.Avoidrepeatedfreeze/thawcycles. PREPARATIONANDUSE: Toreconstitutetheantibody,centrifugetheantibodyvialatmoderatespeed(5,000rpm)for5minutestopellettheprecipitatedantibodyproduct.Carefullyremovetheammoniumsulfate/PBSbuffersolutionanddiscard.Itisnotnecessarytoremovealloftheammoniumsulfate/PBSsolution:10μLofresidualammoniumsulfatesolutionwillnotaffecttheresUSPensionoftheantibody.Donotlettheproteinpelletdry,asseverelossofantibodyreactivitycanoccur. ResuspendtheantibodypelletinasuitableBIOLOGicalbuffersuchasPBSorTBS(pH7.3-7.5)toafinalconcentrationof1.0mg/mL.Forexample,toachievea1.0mg/mLconcentrationwith50μgofprecipitatedantibody,theamountofbufferneededwouldbe50μL. Carefullyaddtheliquidbuffertothepellet.DONOTVORTEX.Mixbygentlestirringwithawidepipettiporgentlefinger-tapping.Lettheprecipitatedantibodyrehydratefor1hourat4-25°Cpriortouse.Smallparticlesofprecipitatedantibodythatfailtoresuspendarenormal.Vialsareoverfilledtocompensateforanylosses. Therehydratedantibodysolutionscanbestoredundilutedat2-8°Cfor2monthswithoutanysignificantlossofactivity.Note,thesolutionisnotsterile,thuscareshouldbetakenifproductisstoredat2-8°C. Forstorageat-20°C,theadditionofanequalvolumeofglycerolcanbeused,however,itisrecommendedthatACSgradeorhigherglycerolbeused,assignificantlossofactivitycanoccuriftheglycerolusedisnotofhighquality. Forlong-termstorageat-70°C,itisrecommendedthattherehydratedantibodysolutionbefurtherdiluted1:1witha2%BSA(fractionV,highest-gradeavailable)solutionmadewiththerehydrationbuffer.Theresulting1%BSA/antibodysolutioncanbealiquotedandstoredfrozenat-70°Cforupto6months.Avoidrepeatedfreeze/thawcycles. |
| BiologicalInformation | |
|---|---|
| Immunogen | Syntheticpeptide,aminoacids26-42ofHuD. |
| Host | Rabbit |
| Specificity | RecognizesHuD.Themolecularweightoftheproteinis41,766Daltons. |
| SpeciesReactivity |
|
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| GeneSymbol |
|
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P26378#Mayplayaroleinneuron-specificRNAprocessing.ProtectsCDKN1AmRNAfromdecaybybindingtoits3"-UTR(Bysimilarity). SIZE:380aminoacids;41760Da SUBUNIT:ComponentofaTAUmRNPcomplex,atleastcomposedofIGF2BP1,ELAVL4andG3BP(Bysimilarity). TISSUESPECIFICITY:Brain. PTM:MethylationatArg-243byCARM1weakensprotectivebindingtothe3"-UTRofCDKN1AmRNAanddown-regulatesCDKN1Aproteinexpression,therebymaintainingcellsinaproliferativestate.MethylationisinhibitedbyNGF,whichfacilitatesneuriteoutgrowth(Bysimilarity). DISEASE:SwissProt:P26378#Paraneoplasticencephalomyelitissensoryneuropathyisassociatedwithsmallcelllungcancerandischaracterizedbydementia,sensoryloss,andotherneurologicaldisABIlities.Itmayresultfromanimmuneresponseprimarilydirectedagainstasmallcelllungtumorantigenwhichismisdirectedagainstsimilarantigensexpressedinbrain. SIMILARITY:SwissProt:P26378##BelongstotheRRMelavfamily.&Contains3RRM(RNArecognitionmotif)domains. |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
联络我们
