Millipore/AB2261 | Anti-Tbr1 Antibody/AB2261/100 µg
市场价：
¥7400.00
美元价：
4440.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB2261 |
| Description | Anti-Tbr1Antibody |
| AlternateNames |
|
| BackgroundInformation | Tbr1geneisamemberofaconservedfamilyofgenesthatshareacommonDNA-bindingdomain,theT-box.T-boxgenesencodetranscriptionfactorsinvolvedintheregulationofdevelopmentalprocesses.Tbr1,aputativetranscriptionfactorknowntobeexpressedinpost-mitoticneurons,hasbeenfoundhighlyexpressedinglutamatergicearly-borncorticalneurons.Asimilarproteinhasbeendisruptedinmiceandshowntobecriticalforearlycorticaldevelopment,andcauseslossofprojectionneuronsintheolfactorybulbsandolfactorycortex.TheC-terminalregiontheTbr1derivedproteinwasfoundtobenecessaryandsufficientforassociationwiththeguanylatekinasedomainofcalcium/calmodulin-dependentserineproteinkinase. |
| ProductInformation | |
|---|---|
| Format | AffinityPurified |
| Control |
|
| Presentation | Purifiedchickenpolyclonalinbuffercontaining0.1MTris-Glycine(pH7.4,150mMNaCl)with0.05%sodiumazide. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Stablefor1yearat2-8°Cfromdateofreceipt. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | KLH-conjugatedlinearpeptidecorrespondingtomouseTbr1. |
| Epitope | Internal |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Chicken |
| Specificity | ThisantibodyrecognizesTbr1. |
| SpeciesReactivity |
|
| SpeciesReactivityNote | Proventoreactwithhuman,mouse,andrat.Predictedtoreactwithhorse,pig,opossum,bovine,andcaninebasedon100%sequencehomology. |
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| GeneSymbol |
|
| PurificationMethod | AffinityPurfied |
| UniProtNumber | |
| UniProtSummary | FUNCTION:Probabletranscriptionalregulatorinvolvedindevelopmentalprocesses.TBR1isrequiredfornormalbraindevelopment. SUBCELLULARLOCATION:NucleusPotential. TISSUESPECIFICTY:Expressedinspecificlaminainthedevelopingandadultbrain. DEVELOPMENTALSTAGE:Firstdetectedaroundday10ofembryonicdevelopmentinthepreplate,atday12.5,inthecorticalplateandintermediatezone,andfromday16.5to18.5,inarostro-caudalgrADIentinthesubplate.Inthethalamus,expressionisfirstobservedatpostnatalstage,P7,andweakexpressioncontinuesinlaterpostnatalandadultstages. SEQUENCESIMILARITIES:Contains1T-boxDNA-bindingdomain. |
| MolecularWeight | ~68kDaisobserved;however,UniProtKB/Swiss-ProtentryQ64336(TBR1_MOUSE)listsamassof73.941kDa. |
| PhysicochemicalInformation |
|---|
| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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