密理博/AB1530 |抗外周蛋白抗体/AB1530/100µ；L
市场价：
¥6980.00
美元价：
4188.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB1530 |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-PeripherinAntibody |
| BackgroundInformation | Peripherinisa56-58kDatypeIIIintermediatefilamentprotein(Portieretal.1983),expressedinmotor,sensoryandsympatheticsystemneuronsaswellasneuroendocrineskincarcinomasandcertainmelanocytictumors.Itisoftenusedanindicatorofentericganglioncelldensityinnormalanddiseased(e.g.Hirschsprung"sdisease)states.AbnormalinclusionscontainingperipherinhavealsobeenreportedinALS.Duringnormal,lateneurogenesisperipherinappearsaftertheexpressionofnestin,vimentin,alpha-internexinandneurofilamentsandisinvolvedinthedifferentiationofneurons,namelyoftheperipheralnervoussystem,andalsoprobablyinaxonalregeneration.Peripherinisnotrelatedtoperipherin-RDS,aphotoreceptorproteinassociatedwithretinaldegenerationandblindness. |
| ProductInformation | |
|---|---|
| Format | Serum |
| Control |
|
| Presentation | Rabbitpolyclonalantisera,nopreservatives. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Stablefor1yearat-20°Cinundilutedaliquotsfromdateofreceipt. HandlingRecommendations:Uponfirstthaw,andpriortoremovingthecap,centrifugethevialandgentlymixthesolution.Aliquotintomicrocentrifugetubesandstoreat-20°C.Avoidrepeatedfreeze/thawcycles,whichmaydamageIgGandaffectproductperformance. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Electrophoreticallypuretrp-E-peripherinfusionprotein[Dev.BrainRes.(1990)57:235-248],containingallbutthe4Nterminalaminoacidsofratperipherin.FusionproteinpurifiedfrombacterialinclusionbodiesbyDEAE-cellulosechromatographyin6MureafollowedbypreparativeSDS-PAGE. |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | RecognizesPeripherin.Theantibodystainsa~57kDabandcleanlyandspecificallyanddoesnotstainvimentin,GFAP,alpha-internexinoranyoftheneurofilamentsubunits.Strongstainingonrat,mouse,human,pigandcowperipherin.Doesnotstainchicken,quailorothermoredistantlyrelatedspecieswhichappeartolackperipherin. |
| SpeciesReactivity |
|
| SpeciesReactivityNote | Strongstainingonratandhuman.Cross-reactswithmouse,pig,andbovine.Otherspeciesnottested. |
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Thisgeneencodesacytoskeletalproteinfoundinneuronsoftheperipheralnervoussystem.TheencodedproteinisatypeIIIintermediatefilamentproteinwithhomologytoothercytoskeletalproteinssuchasdesmin,andisadifferentproteinthattheperipherinfoundinphotoreceptors.Mutationsinthisgenehavebeenassociatedwithsusceptibilitytoamyotrophiclateralsclerosis. |
| GeneSymbol |
|
| PurificationMethod | Unpurified |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P41219#Class-IIIneuronalintermediatefilamentprotein. SIZE:470aminoacids;53651Da SIMILARITY:SwissProt:P41219##Belongstotheintermediatefilamentfamily. |
| MolecularWeight | 56-58kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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