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Millipore/14-828 | HDAC4, active recombinant protein/14-828/1 each

Millipore/14-828 | HDAC4, active recombinant protein/14-828/1 each
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0.00
产品分类:
夹心法ELISA
公司分类:
Sandwich_method_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | 14-828 |
BrandFamily | Upstate |
TradeName |
|
Description | HDAC4,activerecombinantprotein |
Overview | RecominanthumanHDAC4(a.a.627-end)withN-terminalGST-tag |
BackgroundInformation | Histonedeacetylationactsatagforepigeneticrepressionandplaysanimportantroleintranscriptionalregulation,cellcycleprogressionanddevelopmentalevents.HDAC4isahistonedeacetylasewhichdeacetylateslysinesonthecorehistones.HDAC4accumulatesinthenucleiofmyotubes,suggestinginvolvementinmuscledifferentiation.HDAC4doesnotbindDNAdirectlybutinteractswiththemyocyteenhancerfactorsMef2a,Mef2c,andMef2d.HDAC4alsointeractswiththebreastcancer-associatedtranscriptionalrepressorPLU-1/JARID1B,theNr2c1/TR2nuclearreceptor,aswellasthe14-3-3chaperoneprotein,inaphosphorylationdependentmanner.ItalsoformspartofamultiproteincomplexwithRbAp48andHDAC3. |
ProductInformation | |
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Format | Purified |
Presentation | 50μgofrecombinantprotienin50mMTris-HCl,pH7.0,150mMNaCl,0.1mMEDTA,1mMdithiothreitol,20%glycerol.Frozensolution. |
StorageandShippingInformation | |
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StorageConditions | Storeinaliquotsat-70°C.Avoidfreeze/thawcycles.Formaximumrecoveryofproduct,centrifugeoriginalvialpriortoremovingcap. |
Applications | |
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Application | RecominanthumanHDAC4(a.a.627-end)withN-terminalGST-tag. |
KeyApplications |
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ApplicationNotes | HDACdeacetylaseassays |
BIOLOGicalInformation | |
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Concentration | 0.2mg/ml |
Purity | Purity>90%bySDS-PAGEandCoomassiebluestaining. |
Source | ExpressedbybaculovirusinSf9insectcells. |
SpecificActivity | [Varieswithlot.ForSpecificActivitydata,refertotheCertificateofAnalysisforindividuallotsofthisenzyme.]LotR0801D0003:2.7U/mg,whereoneunitofHDAC4activityisdefinedas1nmolofassaysubstrate(HDACassaykit,catalog#17-356)deacetylatedperminuteat37°C. |
EntrezGeneNumber | |
GeneSymbol |
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PurificationMethod | Purifiedusingglutathione-agarose.GSTportionwascleavedbyPreScission™protease. |
UniProtNumber | |
MolecularWeight | 49kDa |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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