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Millipore/04-1032 | Anti-Neurofilament-66 Antibody, clone EP676Y, rabbit monoclonal/04-1032/100 µL
Millipore/04-1032 | Anti-Neurofilament-66 Antibody, clone EP676Y, rabbit monoclonal/04-1032/100 µL
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美元价:
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产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | 04-1032 |
| Description | Anti-Neurofilament-66Antibody,cloneEP676Y,rabbitmonoclonal |
| AlternateNames |
|
| BackgroundInformation | Neurofilament-66,alsoknownasα-internexin,isamemberoftheIFfamily.ItisfoundindevelopingneuroblastsandintheCNSofadults.Neurofilament-66isexpressedintheadultbrainatlowerlevelsthanotherneurofilamentproteins. |
| ProductInformation | |
|---|---|
| Format | Unpurified |
| Control |
|
| Presentation | RabbitMonoclonalinbuffercontaining50mMTris-Glycine(pH7.4),0.15MNaClcontaining40%Glycerol,0.01%sodiumazideand0.05%BSA. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Stablefor1yearat-20ºCfromdateofreceipt. HandlingRecommendations:Uponfirstthaw,andpriortoremovingthecap,centrifugethevialandgentlymixthesolution.Aliquotintomicrocentrifugetubesandstoreat-20°C.Avoidrepeatedfreeze/thawcycles,whichmaydamageIgGandaffectproductperformance.Note:VariABIlityinfreezertemperaturesbelow-20°Cmaycauseglycerolcontainingsolutionstobecomefrozenduringstorage. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | SyntheticpeptidecorrespondingtoresiduesinthetaildomainofhumanNeurofilament-66. |
| Epitope | TailDomain |
| Clone | EP676Y |
| Host | Rabbit |
| Specificity | ThisantibodyrecognizesNeurofilament-66atandaroundthetaildomain. |
| Isotype | IgG |
| SpeciesReactivity |
|
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | NeurofilamentsaretypeIVintermediatefilamentheteropolymerscomposedoflight,medium,andheavychains.Neurofilamentscomprisetheaxoskeletonandtheyfunctionallymaintaintheneuronalcaliber.Theymayalsoplayaroleinintracellulartransporttoaxonsanddendrites.Thisgeneisamemberoftheintermediatefilamentfamilyandisinvolvedinthemorphogenesisofneurons. |
| GeneSymbol |
|
| PurificationMethod | Unpurified |
| UniProtNumber | |
| UniProtSummary | FUNCTION:Class-IVneuronalintermediatefilamentthatisabletoself-assemble.Itisinvolvedinthemorphogenesisofneurons.ItmayformanindependentstructuralnetworkwithouttheinvolvementofotherneurofilamentsoritmaycooperatewithNF-LtoformthefilamentousbackbonetowhichNF-MandNF-Hattachtoformthecross-bridges. TISSUESPECIFICITY:FoundpredominantlyinadultCNS. DEVELOPMENTALSTAGE:Expressedinbrainasearlyasthe16thweekofgestation,andincreasedrapidlyandreachedasteadystatelevelbythe18thweekofgestation. PTM:O-glycosylatedBysimilarity. PhosphorylateduponDNAdamage,probablybyATMorATR. SEQUENCESIMILARITIES:Belongstotheintermediatefilamentfamily. |
| MolecularWeight | ~66kDa |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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