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Millipore/CBL1512Z | Anti-Integrin αM [CD11b] Antibody, clone OX-42/CBL1512Z/100 µg
![Millipore/CBL1512Z | Anti-Integrin αM [CD11b] Antibody, clone OX-42/CBL1512Z/100 µg](https://www.ebiomall.cn/images/millipore/201710/Antibody_STD[Antibody_STD-ALL].jpg)
Millipore/CBL1512Z | Anti-Integrin αM [CD11b] Antibody, clone OX-42/CBL1512Z/100 µg
市场价：
¥5540.00
美元价：
3324.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | CBL1512Z |
| Replaces | MAB1405Z |
| BrandFamily | Chemicon® |
| TradeName |
|
| Description | Anti-IntegrinαM[CD11b]Antibody,cloneOX-42 |
| AlternateNames |
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| ProductInformation | |
|---|---|
| Format | Purified |
| Presentation | TheimmunoglobulinwaspurifiedbyproteinGaffinitychromatographyandispresentedasaliquidinphosphatebufferedsalinecontainingnopreservatives. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintaininundilutedaliquotsat-20°Cforupto12monthsfromdateofreceipt.Avoidrepeatedfreeze/thawcycles. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | Ratperitonealmacrophages |
| Clone | OX-42 |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Mouse |
| Specificity | Thisantibodyrecognizesmostmacrophages(includingresidentperitonealandactivatedmacrophages),Kupffercells,butonlyabout35%ofalveolarmacrophages.Theantibodyalsolabelsdendriticcellsextensively,granulocytesandcellswiththemorphologyofmicrogliainbrain.Theantibodyprecipitatesthreepolypeptidesof150,103and95KDa.TheantibodyinhibitscomplementmediatedrosettesandisprobablytheratequivalentofthehumanreceptorforIC3bcalledCR3.FUSIONPARTNER:NSOmyelomacellline. |
| Isotype | IgG2a |
| SpeciesReactivity |
|
| AntibodyType | MonoclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | ThisgeneencodestheintegrinalphaMchain.Integrinsareheterodimericintegralmembraneproteinscomposedofanalphachainandabetachain.ThisI-domaincontainingalphaintegrincombineswiththebeta2chain(ITGB2)toformaleukocyte-specificintegrinreferredtoasmacrophagereceptor1("Mac-1"),orinactivated-C3b(iC3b)receptor3("CR3").ThealphaMbeta2integrinisimportantintheadherenceofneutrophilsandmonocytestostimulatedendothelium,andalsointhephagocytosisofcomplementcoatedparticles.SomeintegrinalphaMproteinscontainaninsertedaminoacid(Q,betweenAApositions499and500)resultingfroma3bpshiftinaspliceacceptorthatinsertsthecodonCAG;receptorswithorwithouttheextraaminoacidarefunctionallyindistinguishable |
| GeneSymbol |
|
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P11215#Integrinalpha-M/beta-2isimplicatedinvariousadhesiveinteractionsofmonocytes,macrophagesandgranulocytesaswellasinmediatingtheuptakeofcomplement-coatedparticles.ItisidenticalwithCR-3,thereceptorfortheiC3bfragmentofthethirdcomplementcomponent.ItprobablyrecognizestheR-G-DpeptideinC3b.Integrinalpha-M/beta-2isalsoareceptorforfibrinogen,factorXandICAM1.ItrecognizesP1andP2peptidesoffibrinogengammachain. SIZE:1152aminoacids;127179Da SUBUNIT:Heterodimerofanalphaandabetasubunit.Alpha-Massociateswithbeta-2. SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein. TISSUESPECIFICITY:Predominantlyexpressedinmonocytesandgranulocytes. DOMAIN:SwissProt:P11215TheintegrinI-domain(insert)isaVWFAdomain.IntegrinswithI-domainsdonotundergoproteasecleavage. SIMILARITY:Belongstotheintegrinalphachainfamily.&Contains7FG-GAPrepeats.&Contains1VWFAdomain. |
| PhysicochemicalInformation |
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| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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