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当前位置: 首页 > 产品中心 > Functional_antibody > 密理博/FCABS165A6 |密标™ 抗MAPK 1/2(tERK)抗体,Alexa Fluor 647结合物/FCABS165A6/100试验
商品详细密理博/FCABS165A6 |密标™ 抗MAPK 1/2(tERK)抗体,Alexa Fluor 647结合物/FCABS165A6/100试验
密理博/FCABS165A6 |密标™ 抗MAPK 1/2(tERK)抗体,Alexa Fluor 647结合物/FCABS165A6/100试验
密理博/FCABS165A6 |密标™ 抗MAPK 1/2(tERK)抗体,Alexa Fluor 647结合物/FCABS165A6/100试验
商品编号: FCABS165A6
品牌: 密理博
市场价: ¥5340.00
美元价: 3204.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberFCABS165A6
TradeName
  • Milli-Mark
DescriptionMilli-Mark™Anti-MAPK1/2(tERK)Antibody,AlexaFluor647Conjugate
AlternateNames
  • Extracellularsignal-regulatedkinase1
  • ERK-1
  • Insulin-stimulatedMAP2kinase
  • Mitogen-activatedproteinkinase1
  • MAPkinase1
  • MAPK1
  • p44-ERK1
  • ERT2
  • MAPkinaseisoformp44
  • p44
  • MAPK
  • Microtubule-associatedprotein2kinase
  • MNK1
BackgroundInformationTheextracellularsignal-regulatedkinases1and2(ERK1andERK2),alsocalledMAPK1andMAPK2,aremembersoftheMitogenActivatedProteinKinase(MAPK)familyofproteinsfoundinalleukaryotes.Becausethe44kDaERK1andthe42kDaERK2arehighlyhomologousandbothfunctioninthesameproteinkinasecascade,thetwoproteinsareoftenreferredtocollectivelyasERK1/2orMAPK1/2.TheMAPK1/2signalingcascadehasbeenshowntobeacriticalregulatorofcelldifferentiation,cellphysiologyandneuronalfunction.AberrantcontrolofMAPK1/2activityhasbeenimplicatedinavarietyofpathologicalconditions,includingcancerandautoimmunediseases,andefficientstudymethodsareindemand.
ProductInformation
FormatAlexaFluor®647
Control
  • Jurkatcells
PresentationPurifiedrabbitpolyclonalantibodyconjugatedtoAlexaFluor647inPBSbufferwith15mg/mLBSAand0.1%SodiumAzide
StorageandShippingInformation
StorageConditionsMaintainedrefrigeratedat2-8°Cfromdateofreceipt.Protectedfromlightinundilutedaliquotsfor6monthsfromdateofreceipt.
Applications
ApplicationMilli-MarkAnti-MAPK1/2(tERK)Antibody,AlexaFluor647ConjugatedetectslevelofMAPK1/2(tERK)&hasbeenpublished&validatedforuseinFC.
KeyApplications
  • FlowCytometry
BIOLOGicalInformation
ImmunogenKLH-conjugatedlinearpeptidecorrespondingtoratMAPK1/2attheC-terminus.
EpitopeC-terminus
ConcentrationPleaserefertotheCertificateofAnalysisforthelot-specificconcentration.
HostRabbit
SpecificityAntibodyrecognizesMAPK1/2.C-terminus.
SpeciesReactivity
  • Human
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryKinaseinvolvedinintracellularsignalling;componentofMapksignallingpathway[RGD]
GeneSymbol
  • MAPK1
  • p38
  • ERK
  • P42MAPK
  • ERK2
  • p40
  • PRKM1
  • p41mapk
  • PRKM2
  • MAPK2
  • p42-MAPK
  • p41
  • ERK-2
  • ERT1
PurificationMethodProteinAPurfied
UniProtNumber
UniProtSummaryFUNCTION:Involvedinboththeinitiationandregulationofmeiosis,mitosis,andpostmitoticfunctionsindifferentiatedcellsbyphosphorylatinganumberoftranscriptionfactorssuchasELK-1.PhosphorylatesEIF4EBP1;requiredforinitiationoftranslation.Phosphorylatesmicrotubule-associatedprotein2(MAP2).PhosphorylatesSPZ1.Phosphorylatesheatshockfactorprotein4(HSF4)Bysimilarity
MolecularWeight43kDaCalculated
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。