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密理博/FCABS165A6 |密标™ 抗MAPK 1/2(tERK)抗体,Alexa Fluor 647结合物/FCABS165A6/100试验

密理博/FCABS165A6 |密标™ 抗MAPK 1/2(tERK)抗体,Alexa Fluor 647结合物/FCABS165A6/100试验
商品编号:
FCABS165A6
品牌:
密理博
市场价:
¥5340.00
美元价:
3204.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | FCABS165A6 |
TradeName |
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Description | Milli-Mark™Anti-MAPK1/2(tERK)Antibody,AlexaFluor647Conjugate |
AlternateNames |
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BackgroundInformation | Theextracellularsignal-regulatedkinases1and2(ERK1andERK2),alsocalledMAPK1andMAPK2,aremembersoftheMitogenActivatedProteinKinase(MAPK)familyofproteinsfoundinalleukaryotes.Becausethe44kDaERK1andthe42kDaERK2arehighlyhomologousandbothfunctioninthesameproteinkinasecascade,thetwoproteinsareoftenreferredtocollectivelyasERK1/2orMAPK1/2.TheMAPK1/2signalingcascadehasbeenshowntobeacriticalregulatorofcelldifferentiation,cellphysiologyandneuronalfunction.AberrantcontrolofMAPK1/2activityhasbeenimplicatedinavarietyofpathologicalconditions,includingcancerandautoimmunediseases,andefficientstudymethodsareindemand. |
ProductInformation | |
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Format | AlexaFluor®647 |
Control |
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Presentation | PurifiedrabbitpolyclonalantibodyconjugatedtoAlexaFluor647inPBSbufferwith15mg/mLBSAand0.1%SodiumAzide |
StorageandShippingInformation | |
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StorageConditions | Maintainedrefrigeratedat2-8°Cfromdateofreceipt.Protectedfromlightinundilutedaliquotsfor6monthsfromdateofreceipt. |
Applications | |
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Application | Milli-MarkAnti-MAPK1/2(tERK)Antibody,AlexaFluor647ConjugatedetectslevelofMAPK1/2(tERK)&hasbeenpublished&validatedforuseinFC. |
KeyApplications |
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BIOLOGicalInformation | |
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Immunogen | KLH-conjugatedlinearpeptidecorrespondingtoratMAPK1/2attheC-terminus. |
Epitope | C-terminus |
Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
Host | Rabbit |
Specificity | AntibodyrecognizesMAPK1/2.C-terminus. |
SpeciesReactivity |
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AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | Kinaseinvolvedinintracellularsignalling;componentofMapksignallingpathway[RGD] |
GeneSymbol |
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PurificationMethod | ProteinAPurfied |
UniProtNumber | |
UniProtSummary | FUNCTION:Involvedinboththeinitiationandregulationofmeiosis,mitosis,andpostmitoticfunctionsindifferentiatedcellsbyphosphorylatinganumberoftranscriptionfactorssuchasELK-1.PhosphorylatesEIF4EBP1;requiredforinitiationoftranslation.Phosphorylatesmicrotubule-associatedprotein2(MAP2).PhosphorylatesSPZ1.Phosphorylatesheatshockfactorprotein4(HSF4)Bysimilarity |
MolecularWeight | 43kDaCalculated |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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