密理博/HT17MG-14K-PX25 |密理博MAP人TH17磁珠板预混-25 Plex-免疫学
商品编号：
HT17MG-14K-PX25
品牌：
密理博
市场价：
¥78080.00
美元价：
46848.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Description | |
|---|---|
| CatalogueNumber | HT17MG-14K-PX25 |
| TradeName |
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| Description | MILLIPLEXMAPHumanTH17MagneticBeadPanelPremixed-25Plex-ImmunologyMultiplexAssay |
| Overview | EMDMillipore’sMILLIPLEX®MAPHumanTH17PremixedMagneticBeadPanelisa25-plexkittobeusedforthesimultaneousquantificationofthefollowinganalytesinserum,plasmaorculturesupernatantsamples:GM-CSF,IFN-γ,IL-1β,IL-2,IL-4,IL-5,IL-6,IL-9,IL-10,IL-12(p70),IL-13,IL-15,IL-17A,IL-17F,IL-17E/IL-25,IL-21,IL-22,IL-23,IL-27,IL-28A,IL-31,IL-33,MIP-3α/CCL20,TNF-αandTNFβ. MILLIPLEX®MAPoffersthebroadestselectionofanalytesacrossawiderangeofdiseasestatesandspecies.Oncetheanalytesofinteresthavebeenidentified,youcanrelyonthequalitythatwebuildintoeachkittoproduceresultsyoucantrust.Inadditiontotheassaycharacteristicslistedintheprotocol,otherperformancecriteriaevaluatedduringthevalidationprocessinclude:cross-reactivity,dilutionlinearity,kitstABIlityandsamplebehavior(e.g.detectabilityandstability).Eachpanelandkitmeetsstringentmanufacturingcriteriatoensurebatch-to-batchreproducibility. EachMILLIPLEX®MAPpanelandkitincludes: •Qualitycontrols(QCs)providedtoqualifyassayperformance •Comparisonofstandard(calibrator)andQClotstoareferencelottoensurelot-to-lotconsistency •Optimizedserummatrixtomimicnativeanalyteenvironment •Detectionantibodycocktailsdesignedtoyieldconsistentanalyteprofileswithinpanel MILLIPLEX®MAPoffersyou: oTheabilitytochooseanycombinationofanalytesfromourpanelofsevenanalytestodesignacustomkitthatbettermeetsyourneeds. oAconvenient“all-in-one”boxformatthatgivesyoutheassurancethatyouwillhaveallthenecessaryreagentsyouneedtorunyourassay. EMDMillipore’sMILLIPLEX®MAPHumanTH17MagneticBeadPremixedPanelispartofthemostversatilesystemavailableforcytokineresearch.FromoursingletomultiplexbioMarkersolutions,wepartnerwithyoutodesign,develop,analyticallyvalidateandbuildthemostcomprehensivelibraryavailableforproteindetectionandquantitation. |
| BackgroundInformation | CD4T-helpercellsaremajorplayersinadaptiveimmunity.Basedontheirexpressionprofileoftranscriptionfactorsandsecretedcytokines,thesecellsaredividedintothemajorsubsetsTh1,Th2,Th17andTregulatory(Treg)cells.Th1cells,inducedbyIL-12andenhancedbyIFNγ,secreteIFNγthatactivatesmacrophages.InducedbyIL-4,Th2cellsprimarilyproduceIL-4,IL-5,IL-13,IL-25andIL-17E,playingaroleinallergy.Tregcells,inducedbyTGFβ,producetheanti-inflammatorycytokinesIL-10andTGFβandfunctiontocontrolT-cellresponsestopreventautoimmunereactions.Th17cells,amorerecentlydiscoveredsubsetcharacterizedbytheproductionofIL-17,areinducedbyTGFβcombinedwithIL-23andIL-1βinhumans,andTGFβ,IL-6andIL-21inmice.ActivatedTh17cellssecreteIL-17A,IL-17F,IL-21,IL-22andTNFαtopromotetissueinflammation. Th17cellsareinvolvedintheclearanceofextracellularbacteriaandfungi.TheyareabundantintheintestinallaminapropriaandfunctionasabarrieragainstinvADIngpathogens.ExcessiveamountsofTh17cellshavebeenimplicatedinthepathogenesisofseveralautoimmunediseases,includingmultiplesclerosis,psoriasis,juvenilediabetes,rheumatoidarthritis,Crohn"sdiseaseandautoimmuneuveitis.Inaddition,Th17cellsplayanimportantroleintumordevelopment,progressionandmetastasis,potentiallyinbothpromotingandinhibitingtumorgrowth. TheMILLIPLEX®MAPHumanTH17MagneticBeadPanelenablesyoutofocusontherelevanceandtherapeuticpotentialofthemodulationofCD4T-helpercellcytokinesinyourresearchmodel.CoupledwiththeLuminexxMAP®platforminamagneticbeadformat,youreceivetheadvantageofidealspeedandsensitivity,allowingquantitativemultiplexdetectionofmultipleanalytessimultaneously,whichcandramaticallyimproveproductivity. |
| ProductInformation | |
|---|---|
| Detectionmethod | LuminexxMAP |
| Configuration | Premixed |
| Precision,% |
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| PanelType | MAGNETICCytokines/Chemokines |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Recommendedstorageforkitcomponentsis2-8°C. |
| BIOLOGicalInformation | |
|---|---|
| SpeciesReactivity |
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| AnalytesAvailable |
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| CrossReactivity | Cross-reactivitybetweentheantibodiesandanyoftheotheranalytesinthispanelisnon-detectableornegligIBLe. |
| Accuracy |
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| Dimensions |
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| MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年，总部位于美国麻省，在全世界设有47个办事处，为100多个国家提供产品和技术服务。目前全球雇员超过5800人，在美国、法国和日本等国家拥有7家大型生产工厂，主要生产过滤膜及膜过滤产品。20世纪80年代，密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构，并于2000年4月在上海浦东外高桥保税区建立了密理博（上海）贸易有限公司。为了更好地满足中国用户的需求，密理博中国主页于2006年11月向广大用户开放，介绍密理博中国有限公司的最新动态，力求为用户打造专业的产品与服务信息交流平台。
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