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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/IHCR1001-6 | Anti-Neuron-Specific Nuclear Protein Antibody, prediluted, clone A60/IHCR1001-6/6 mL
商品详细Millipore/IHCR1001-6 | Anti-Neuron-Specific Nuclear Protein Antibody, prediluted, clone A60/IHCR1001-6/6 mL
Millipore/IHCR1001-6 | Anti-Neuron-Specific Nuclear Protein Antibody, prediluted, clone A60/IHCR1001-6/6 mL
Millipore/IHCR1001-6 | Anti-Neuron-Specific Nuclear Protein Antibody, prediluted, clone A60/IHCR1001-6/6 mL
商品编号: IHCR1001-6
品牌: 密理博
市场价: ¥5740.00
美元价: 3444.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberIHCR1001-6
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-Neuron-SpecificNuclearProteinAntibody,prediluted,cloneA60
AlternateNames
  • NeuN
BackgroundInformationNeuNantibody(NEUronalNuclei;cloneA60)specificallyrecognizestheDNA-binding,neuron-specificproteinNeuN,whichispresentinmostCNSandPNSneuronalcelltypesofallvertebratestested.NeuNproteindistributionsareapparentlyrestrictedtoneuronalnuclei,perikaryaandsomeproximalneuronalprocessesinbothfetalandadultbrainalthough,someneuronsfailtoberecognizedbyNeuNatallages:INLretinalcells,Cajal-Retziuscells,Purkinjecells,inferiorolivaryanddentatenucleusneurons,andsympatheticganglioncellsareexamples(Mullenetal.,1992;Wolfetal.,1996).ImmunohistochemicallydetectableNeuNproteinfirstappearsatdevelopmentaltimepointsthatcorrespondwiththewithdrawaloftheneuronfromthecellcycleand/orwiththeinitiationofterminaldifferentiationoftheneuron(Mullenetal.,1992).ImmunoreactivityappearsaroundE9.5inthemouseneuraltubeandisextensivethroughoutthedevelopingnervoussystembyE12.5.Strongnuclearstainingsuggestsanuclearregulatoryproteinfunction;however,noevidencecurrentlyexistsastowhethertheNeuNproteinantigenhasafunctioninthedistalcytoplasmorwhetheritismerelysynthesizedtherebeforebeingtransportedbackintothenucleus.Nodifferencebetweenproteinisolatedfrompurifiednucleiandwholebrainextractonimmunoblotshasbeenfound(Mullenetal.,1992).
ProductInformation
FormatPurified
PresentationLiquiddilutedinPBS,pH7.2withstABIlizers,0.2%Tween20,and0.1%ProClin300aspreservative.
StorageandShippingInformation
StorageConditionsMaintainat2-8°C.Refertovialforexpirationdating.
Applications
ApplicationAnti-Neuron-SpecificNuclearProteinAntibody,prediluted,cloneA60detectslevelofNeuron-SpecificNuclearProtein&hasbeenpublished&validatedforuseinIH(P).
KeyApplications
  • Immunohistochemistry(Paraffin)
ApplicationNotesAntibodyispredilutedandreadytouseforImmunohistochemistryofformalin-fixed,paraffin-embeddedtissues.

Pretreatment:HeatInducedEpitopeRetrieval(HIER).RecommendCitrateBuffer,pH6.0(Cat.No.21545).NosignalwasdetectedwithoutEpitoperetrieval.

Incubation:30minuteswithIHCSelect®DetectionKits.

NeuN,hasbeenpredilutedforuseastheprimaryantibodywithChemicon"sIHCSelect®DetectionKitsandProtocols(CatalogNos.DAB050,DET-HP1000,APR050,andDET-APR1000),butothersupplier"sIHCdetectionsystemsmaybeused.Foroptimizedprotocoldetails,visitwww.chemicon.comandselecttheprotocolslinkunderCat.No.IHCR1001-6.
BIOLOGicalInformation
ImmunogenPurifiedcellnucleifrommousebrain.
CloneA60
HostMouse
Specificityneuron-specificproteinNeuN
SpeciesReactivity
  • Avian
  • Chicken
  • Ferret
  • Human
  • Mouse
  • Pig
  • Rat
  • Primate
  • Salamander
  • Vertebrates
AntibodyTypeMonoclonalAntibody
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。