
微孔/04-460 |抗CD3ε抗体,兔单克隆/04-460/100µ;L
市场价:
¥0.00
美元价:
0.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description | |
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CatalogueNumber | 04-460 |
BrandFamily | Upstate |
TradeName |
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Description | Anti-CD3εAntibody,rabbitmonoclonal |
ProductInformation | |
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Format | Purified |
Presentation | 100μLofrabbitmonoclonalIgGin60%storagebuffer(50mMTris-Glycine(pH7.4),0.15MNaCl,0.01%sodiumazideand0.05%BSA)and40%glycerol. |
StorageandShippingInformation | |
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StorageConditions | 2yearsat-20°Cfromdateofshipment.Uponfirstthaw,andpriortoremovingthecap,centrifugethevialandgentlymixthesolution.Aliquotintomicrocentrifugetubesandstoreat-20°C.Avoidrepeatedfreeze/thawcycles,whichmaydamageIgGandaffectproductperformance.Note:VariABIlityinfreezertemperaturesbelow-20°Cmaycauseglycerol-containingsolutionstobecomefrozenduringstorage. |
BIOLOGicalInformation | |
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Immunogen | KLH-conjugatedsyntheticpeptidecomposedofresiduesencompassingthecytoplasmicdomainofhumanCD3. |
Host | Rabbit |
Specificity | RecognizesaregioncomposedofresiduesencompassingthecytoplasmicdomainofhumanCD3.ThisantibodydoesnotrecognizetheothersubunitsofCD3. |
Isotype | IgG |
SpeciesReactivity |
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AntibodyType | MonoclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | TheproteinencodedbythisgeneistheCD3-epsilonpolypeptide,whichtogetherwithCD3-gamma,-deltaand-zeta,andtheT-cellreceptoralpha/betaandgamma/deltaheterodimers,formstheT-cellreceptor-CD3complex.Thiscomplexplaysanimportantroleincouplingantigenrecognitiontoseveralintracellularsignal-transductionpathways.Thegenesencodingtheepsilon,gammaanddeltapolypeptidesarelocatedinthesameclusteronchromosome11.TheepsilonpolypeptideplaysanessentialroleinT-celldevelopment.Defectsinthisgenecauseimmunodeficiency.ThisgenehasalsobeenlinkedtoasusceptibilitytotypeIdiabetesinwomen. |
GeneSymbol |
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UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:P07766#TheCD3complexmediatessignaltransduction. SIZE:207aminoacids;23147Da SUBUNIT:TheTCR/CD3complexofT-lymphocytesconsistsofeitheraTCRalpha/betaorTCRgamma/deltaheterodimercoexpressedatthecellsurfacewiththeinvariantsubunitsofCD3labeledgamma,delta,epsilon,zeta,andeta. SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein. SIMILARITY:SwissProt:P07766##Contains1Ig-like(immunoglobulin-like)domain.&Contains1ITAMdomain. |
MolecularWeight | 23kDa |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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