4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:分子类,蛋白类,抗体类,生化类试剂
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Functional_antibody > 微孔/04-460 |抗CD3ε抗体,兔单克隆/04-460/100µ;L
商品详细微孔/04-460 |抗CD3ε抗体,兔单克隆/04-460/100µ;L
微孔/04-460 |抗CD3ε抗体,兔单克隆/04-460/100µ;L
微孔/04-460 |抗CD3ε抗体,兔单克隆/04-460/100µ;L
商品编号: 04-460
品牌: 密理博
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumber04-460
BrandFamilyUpstate
TradeName
  • Upstate
DescriptionAnti-CD3εAntibody,rabbitmonoclonal
ProductInformation
FormatPurified
Presentation100μLofrabbitmonoclonalIgGin60%storagebuffer(50mMTris-Glycine(pH7.4),0.15MNaCl,0.01%sodiumazideand0.05%BSA)and40%glycerol.
StorageandShippingInformation
StorageConditions2yearsat-20°Cfromdateofshipment.Uponfirstthaw,andpriortoremovingthecap,centrifugethevialandgentlymixthesolution.Aliquotintomicrocentrifugetubesandstoreat-20°C.Avoidrepeatedfreeze/thawcycles,whichmaydamageIgGandaffectproductperformance.Note:VariABIlityinfreezertemperaturesbelow-20°Cmaycauseglycerol-containingsolutionstobecomefrozenduringstorage.
Applications
ApplicationPleasenotethatthisproductwillnotbeavailableforsaleafterMarch15,2015.Pleaseselectoneoftheotherantibodiesagainstthistarget.DetectCD3εusingthisAnti-CD3εAntibody,RabbitvalidatedforuseinIF&WB.
KeyApplications
  • Immunofluorescence
  • WesternBlotting
BIOLOGicalInformation
ImmunogenKLH-conjugatedsyntheticpeptidecomposedofresiduesencompassingthecytoplasmicdomainofhumanCD3.
HostRabbit
SpecificityRecognizesaregioncomposedofresiduesencompassingthecytoplasmicdomainofhumanCD3.ThisantibodydoesnotrecognizetheothersubunitsofCD3.
IsotypeIgG
SpeciesReactivity
  • Human
AntibodyTypeMonoclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryTheproteinencodedbythisgeneistheCD3-epsilonpolypeptide,whichtogetherwithCD3-gamma,-deltaand-zeta,andtheT-cellreceptoralpha/betaandgamma/deltaheterodimers,formstheT-cellreceptor-CD3complex.Thiscomplexplaysanimportantroleincouplingantigenrecognitiontoseveralintracellularsignal-transductionpathways.Thegenesencodingtheepsilon,gammaanddeltapolypeptidesarelocatedinthesameclusteronchromosome11.TheepsilonpolypeptideplaysanessentialroleinT-celldevelopment.Defectsinthisgenecauseimmunodeficiency.ThisgenehasalsobeenlinkedtoasusceptibilitytotypeIdiabetesinwomen.
GeneSymbol
  • CD3E
  • T3E
  • TCRE
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:P07766#TheCD3complexmediatessignaltransduction.
SIZE:207aminoacids;23147Da
SUBUNIT:TheTCR/CD3complexofT-lymphocytesconsistsofeitheraTCRalpha/betaorTCRgamma/deltaheterodimercoexpressedatthecellsurfacewiththeinvariantsubunitsofCD3labeledgamma,delta,epsilon,zeta,andeta.
SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein.
SIMILARITY:SwissProt:P07766##Contains1Ig-like(immunoglobulin-like)domain.&Contains1ITAMdomain.
MolecularWeight23kDa
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。