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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/CBL1337 |抗PECAM-1抗体,克隆390/CBL1337/500µ;G
商品详细Millipore/CBL1337 |抗PECAM-1抗体,克隆390/CBL1337/500µ;G
Millipore/CBL1337 |抗PECAM-1抗体,克隆390/CBL1337/500µ;G
Millipore/CBL1337 |抗PECAM-1抗体,克隆390/CBL1337/500µ;G
商品编号: CBL1337
品牌: 密理博
市场价: ¥6780.00
美元价: 4068.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberCBL1337
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-PECAM-1Antibody,clone390
AlternateNames
  • CD31
BackgroundInformationCD31,alsoknownasplateletendothelialcelladhesionmolecule1(PECAM1)isatypeIintegralmembraneglycoprotein,andamemberoftheimmunoglobulinsuperfamilyofcellsurfacereceptors.PECAM-1isconstitutivelyexpressedonthesurfaceofendothelialcellswhereitisconcentratedatcelljunctions.PECAM-1isalsoexpressedatlowlevelsonallleukocytesandplatelets.HomotypicinteractionofCD31isimportantincell-cellinteraction,cell-matrixinteractionandsignaltransduction.
ProductInformation
FormatPurified
Control
  • JurkatandRajicells,tonsiltissue
PresentationProteinAPurifiedmouseimmunoglobulinin100mMboratebufferedsaline,pH8.0,containingnopreservative.
StorageandShippingInformation
StorageConditionsMaintainfor1yearat2–8°Cfromdateofshipment.Aliquottoavoidrepeatedfreezingandthawing.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap.
Applications
ApplicationAnti-PECAM-1Antibody,clone390isanantibodyagainstPECAM-1foruseinFC,IH&IP.
KeyApplications
  • FlowCytometry
  • Immunohistochemistry
  • Immunoprecipitation
  • AffectsFunction
ApplicationNotesFlowCytometry:1μg/10e6cells.

Immunohistochemistry:acteonefixedfrozentissuesections

Immunoprecipitation

Blockingofcelladhesion:CBL1337inhibitsaggregationofLcellstransfectedwithavariantformofCD31(DeLisser,1993)

Optimalworkingdilutionsmustbedeterminedbytheenduser.
BIOLOGicalInformation
ImmunogenMouseleukocytecellline32D
Clone390
ConcentrationPleaserefertotheCertificateofAnalysisforthelot-specificconcentration.
HostRat
SpecificityCBL1337recognizesmousePECAM-1,a130-140kDatype1integralmembraneglycoprotein.ThisantibodyhasbeenshowntoinhibittheaggregationofLcellstransfectedwithavariantformofPECAM-1(DeLisser,1993).
IsotypeIgG2aκ
SpeciesReactivity
  • Mouse
AntibodyTypeMonoclonalAntibody
EntrezGeneNumber
GeneSymbol
  • PECAM1
  • EndoCAM
  • GPIIA
  • PECAM-1
  • CD31
  • CD31/EndoCAM
PurificationMethodProteinAPurfied
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:P16284#Thisproteinisacelladhesionmoleculeexpressedonplateletsandatendothelialcellintercellularjunctions.
SIZE:738aminoacids;82536Da
SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein.
TISSUESPECIFICITY:Longisoformpredominatesalltissuesexamined,isoformDelta12wasdetectedonlyintracheaandisoformDelta14-15onlyinlung,isoformDelta14wasdetectedinalltissuesexaminedwiththestrongestexpressioninheart.
PTM:PhosphorylatedonSerandTyrresiduesaftercellularactivation.
SIMILARITY:SwissProt:P16284##Contains6Ig-likeC2-type(immunoglobulin-like)domains.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。