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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/04-1074 | Anti-PECAM-1 [CD31] Antibody, clone EP3095, rabbit monoclonal/04-1074/100 µL
商品详细Millipore/04-1074 | Anti-PECAM-1 [CD31] Antibody, clone EP3095, rabbit monoclonal/04-1074/100 µL
Millipore/04-1074 | Anti-PECAM-1 [CD31] Antibody, clone EP3095, rabbit monoclonal/04-1074/100 µL
Millipore/04-1074 | Anti-PECAM-1 [CD31] Antibody, clone EP3095, rabbit monoclonal/04-1074/100 µL
商品编号: 04-1074
品牌: 密理博
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumber04-1074
DescriptionAnti-PECAM-1[CD31]Antibody,cloneEP3095,rabbitmonoclonal
AlternateNames
  • CD31antigen
  • PECAM-1
  • CD31/EndoCAM,adhesionmolecule
BackgroundInformationCD31,alsoknownasplateletendothelialcelladhesionmolecule1(PECAM1)isatypeIintegralmembraneglycoprotein,andamemberoftheimmunoglobulinsuperfamilyofcellsurfacereceptors.PECAM-1isconstitutivelyexpressedonthesurfaceofendothelialcellswhereitisconcentratedatcelljunctions.PECAM-1isalsoexpressedatlowlevelsonallleukocytesandplatelets.HomotypicinteractionofCD31isimportantincell-cellinteraction,cell-matrixinteractionandsignaltransduction.
ProductInformation
FormatUnpurified
Control
  • THP-1andJurkatcelllysates
PresentationRabbitMonoclonalinbuffercontaining50mMTris-Glycine(pH7.4),0.15MNaClcontaining40%Glycerol,0.01%sodiumazideand0.05%BSA.
StorageandShippingInformation
StorageConditionsStablefor1yearat-20ºCfromdateofreceipt.
HandlingRecommendations:Uponreceipt,andpriortoremovingthecap,centrifugethevialandgentlymixthesolution.Aliquotintomicrocentrifugetubesandstoreat-20°C.Avoidrepeatedfreeze/thawcycles,whichmaydamageIgGandaffectproductperformance.Note:VariABIlityinfreezertemperaturesbelow-20°Cmaycauseglycerolcontainingsolutionstobecomefrozenduringstorage.
Applications
ApplicationPleasenotethatthisproductwillnotbeavailableforsaleafterMarch15,2015.Pleaseselectoneoftheotherantibodiesagainstthistarget.Anti-PECAM-1[CD31]Antibody,cloneEP3095,RabbitdetectslevelofPECAM-1[CD31]&hasbeenpublished&validatedforuseinWB,IH(P),FC.
KeyApplications
  • WesternBlotting
  • Immunohistochemistry(Paraffin)
  • FlowCytometry
ApplicationNotesImmunohistochemistryAnalysis:1:250-500dilutionfromapreviouslotdetectedPECAM1inhumanuterusandtonsiltissue.

FlowCytometry:1:70dilutionfromapreviouslotwasusedonFC.
BIOLOGicalInformation
ImmunogenSyntheticpeptidecorrespondingtoresiduesonhumanPECAM-1.
CloneEP3095
HostRabbit
SpecificityThisantibodyrecognizesPECAM1.
IsotypeIgG
SpeciesReactivity
  • Human
AntibodyTypeMonoclonalAntibody
EntrezGeneNumber
GeneSymbol
  • CD31
  • CD31/EndoCAM
  • EndoCAM
  • GPIIA
  • PECAM-1
PurificationMethodUnpurified
UniProtNumber
UniProtSummaryFUNCTION:Thisproteinisacelladhesionmoleculeexpressedonplateletsandatendothelialcellintercellularjunctions.

SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein.

TISSUESPECIFICITY:Longisoformpredominatesalltissuesexamined,isoformDelta12wasdetectedonlyintracheaandisoformDelta14-15onlyinlung,isoformDelta14wasdetectedinalltissuesexaminedwiththestrongestexpressioninheart.

PTM:PhosphorylatedonSerandTyrresiduesaftercellularactivation.

SEQUENCESIMILARITIES:Contains6Ig-likeC2-type(immunoglobulin-like)domains.

MolecularWeight130kDa
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。