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当前位置: 首页 > 产品中心 > Functional_antibody > Millipore/AB2040 | Anti-Fibronectin Antibody/AB2040/100 µg
商品详细Millipore/AB2040 | Anti-Fibronectin Antibody/AB2040/100 µg
Millipore/AB2040 | Anti-Fibronectin Antibody/AB2040/100 µg
Millipore/AB2040 | Anti-Fibronectin Antibody/AB2040/100 µg
商品编号: AB2040
品牌: 密理博
市场价: ¥6780.00
美元价: 4068.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
CatalogueNumberAB2040
BrandFamilyChemicon®
TradeName
  • Chemicon
DescriptionAnti-FibronectinAntibody
ProductInformation
FormatPurified
PresentationIgGfraction.Nopreservatives.Liquidcontaining0.01MPhosphate,0.09MNaCl,pH7.2.
StorageandShippingInformation
StorageConditionsMaintainfrozenat-20°Cforupto12monthsfromdateofreceipt.Avoidrepeatedfreeze/thawcycles.
Applications
ApplicationAnti-FibronectinAntibodyisanantibodyagainstFibronectinforuseinELISA,RIA,IH.
KeyApplications
  • ELISA
  • RADIoimmunoassay
  • Immunohistochemistry
ApplicationNotesImmunohistochemistry:1:80dilutionforimmunofluorescentstainingoffrozenratskinandlivertissues.

Radioimmunoassay

ELISA

Optimalworkingdilutionsmustbedeterminedbyenduser.
BIOLOGicalInformation
ImmunogenFibronectinextractedandpurifiedfromratplasma.
ConcentrationPleaserefertotheCertificateofAnalysisforthelot-specificconcentration.
HostRabbit
SpecificityAntibodyshowslessthan0.1%reactivitywithratCollagenTypesI,II,III,VandratElastinbyradioimmunoassay.
SpeciesReactivity
  • Rat
AntibodyTypePolyclonalAntibody
EntrezGeneNumber
EntrezGeneSummaryThisgeneencodesfibronectin,aglycoproteinpresentinasolubledimericforminplasma,andinadimericormultimericformatthecellsurfaceandinextracellularmatrix.Fibronectinisinvolvedincelladhesionandmigrationprocessesincludingembryogenesis,woundhealing,bloodcoagulation,hostdefense,andmetastasis.Thegenehasthreeregionssubjecttoalternativesplicing,withthepotentialtoproduce20differenttranscriptvariants.However,thefull-lengthnatureofsomevariantshasnotbeendetermined.
GeneSymbol
  • FN1
  • DKFZp686O13149
  • DKFZp686H0342
  • DKFZp686I1370
  • MSF
  • FN
  • CIG
  • DKFZp686F10164
  • LETS
  • FINC
UniProtNumber
UniProtSummaryFUNCTION:SwissProt:P02751#Fibronectinsbindcellsurfacesandvariouscompoundsincludingcollagen,fibrin,heparin,DNA,andactin.Fibronectinsareinvolvedincelladhesion,cellmotility,opsonization,woundhealing,andmaintenanceofcellshape.InteractionwithTNRmediatesinhibitionofcelladhesionandneuriteoutgrowth(Bysimilarity).
SIZE:2386aminoacids;262607Da
SUBUNIT:Mostlyheterodimersormultimersofalternativelysplicedvariants,connectedby2disulfidebondsnearthecarboxylends;toalesserextenthomodimers.InteractswithFBLN1,AMBP,TNR,LGALS3BPandCOL13A1.
SUBCELLULARLOCATION:Secreted,extracellularspace,extracellularmatrix.
TISSUESPECIFICITY:PlasmaFN(solubledimericform)issecretedbyhepatocytes.CellularFN(dimericorcross-linkedmultimericforms),madebyfibroblasts,epithelialandothercelltypes,isdepositedasfibrilsintheextracellularmatrix.Ugl-Y1,Ugl-Y2andUgl-Y3arefoundinurine.DEVELOPMENTALSTAGE:Ugl-Y1,Ugl-Y2andUgl-Y3arepresentintheurinefrom0to17yearsofage.
PTM:Sulfated.
SIMILARITY:SwissProt:P02751##Contains12fibronectintype-Idomains.&Contains2fibronectintype-IIdomains.&Contains16fibronectintype-IIIdomains.
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
品牌介绍
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。